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Young-Joon Surh Selected Research

Glutamate-Cysteine Ligase

3/2021Protective Effects of Taurine Chloramine on Experimentally Induced Colitis: NFκB, STAT3, and Nrf2 as Potential Targets.
1/2020Nuclear Factor Erythroid-Derived 2-Like 2-Induced Reductive Stress Favors Self-Renewal of Breast Cancer Stem-Like Cells via the FoxO3a-Bmi-1 Axis.
7/2019Cellular adaptation mediated through Nrf2-induced glutamate cysteine ligase up-regulation against oxidative stress caused by iron overload in β-thalassemia/HbE patients.
8/2011Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells.
4/2008Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG.

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Young-Joon Surh Research Topics

Disease

142Neoplasms (Cancer)
11/2022 - 01/2002
83Carcinogenesis
05/2022 - 01/2003
58Inflammation (Inflammations)
03/2022 - 01/2002
41Breast Neoplasms (Breast Cancer)
03/2022 - 02/2003
18Colitis
03/2022 - 01/2009
16Colonic Neoplasms (Colon Cancer)
01/2022 - 07/2004
15Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 10/2006
13Neoplasm Metastasis (Metastasis)
01/2022 - 01/2007
12Pheochromocytoma
08/2011 - 04/2003
9Stomach Neoplasms (Stomach Cancer)
06/2021 - 01/2003
7Hypoxia (Hypoxemia)
01/2021 - 11/2006
6Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 11/2002
6Papilloma (Papillomatosis)
06/2011 - 08/2002
6Alzheimer Disease (Alzheimer's Disease)
01/2007 - 11/2002
6Amyloid Plaque
06/2005 - 11/2002
5Infections
06/2021 - 01/2003
5Adenoma (Adenomas)
01/2021 - 07/2013
4Hyperplasia
06/2021 - 03/2008
4Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
03/2018 - 01/2007
4Peritonitis
01/2018 - 09/2013
4Leukemia
12/2007 - 05/2002
4Edema (Dropsy)
02/2005 - 08/2002
3Triple Negative Breast Neoplasms
01/2022 - 12/2019
3Adenocarcinoma
01/2021 - 01/2003

Drug/Important Bio-Agent (IBA)

37Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2021 - 08/2002
30Proteins (Proteins, Gene)FDA Link
11/2022 - 05/2002
29Transcription Factors (Transcription Factor)IBA
05/2022 - 01/2002
26NF-kappa B (NF-kB)IBA
04/2011 - 01/2002
21Dextran SulfateIBA
03/2022 - 01/2008
18EnzymesIBA
01/2021 - 02/2003
18AntioxidantsIBA
12/2020 - 02/2003
15PhytochemicalsIBA
11/2022 - 09/2003
15Heme Oxygenase-1IBA
03/2022 - 12/2008
15Messenger RNA (mRNA)IBA
01/2022 - 01/2002
15AzoxymethaneIBA
01/2021 - 01/2008
14Transcription Factor AP-1 (Transcription Factor AP 1)IBA
05/2013 - 05/2002
13Phosphotransferases (Kinase)IBA
01/2022 - 11/2003
13Reactive Oxygen Species (Oxygen Radicals)IBA
01/2020 - 11/2002
12ProstaglandinsIBA
01/2021 - 10/2003
12ResveratrolIBA
01/2020 - 04/2003
11CytokinesIBA
03/2022 - 01/2003
1115-deoxyprostaglandin J2IBA
09/2021 - 12/2006
11CurcuminIBA
12/2020 - 05/2002
11CarcinogensIBA
11/2015 - 08/2002
10Estrogens (Estrogen)FDA Link
01/2021 - 10/2004
10Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2019 - 08/2002
9Phorbol EstersIBA
10/2014 - 05/2002
8Amyloid beta-PeptidesIBA
01/2007 - 11/2002
7Drinking WaterIBA
03/2022 - 01/2008
7PolyphenolsIBA
03/2018 - 11/2004
7anthraceneIBA
03/2012 - 01/2002
6Sirtuin 1IBA
01/2022 - 10/2012
6LipidsIBA
01/2021 - 12/2003
6STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2021 - 01/2016
6Docosahexaenoic AcidsIBA
01/2021 - 09/2013
6GenisteinIBA
12/2019 - 02/2003
6Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
10/2005 - 02/2003
5Estrogen ReceptorsIBA
03/2022 - 01/2019
5LigandsIBA
03/2021 - 11/2006
5Glutamate-Cysteine LigaseIBA
03/2021 - 04/2008
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 08/2005
515-hydroxyprostaglandin dehydrogenaseIBA
11/2020 - 11/2011
5Celecoxib (Celebrex)FDA Link
03/2020 - 05/2004
5Glutathione (Reduced Glutathione)IBA
01/2020 - 05/2004
5Pharmaceutical PreparationsIBA
04/2019 - 05/2004
5Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
05/2013 - 10/2006
5Nitric Oxide (Nitrogen Monoxide)FDA Link
05/2012 - 12/2003
5TeaIBA
06/2010 - 01/2004
5PPAR gammaIBA
12/2008 - 10/2003
5Capsaicin (Zostrix)FDA Link
05/2007 - 08/2002
5Peptides (Polypeptides)IBA
06/2005 - 11/2002
4cyclopentenoneIBA
09/2021 - 10/2003
4ChemokinesIBA
01/2021 - 01/2003
4sodium sulfate (sodium bisulfate)FDA LinkGeneric
01/2021 - 07/2013
4Dextrans (Dextran)FDA Link
01/2021 - 07/2013
4Proliferating Cell Nuclear Antigen (PCNA)IBA
01/2020 - 02/2006
4ginsenoside Rg3IBA
07/2019 - 02/2003
4ZymosanIBA
01/2018 - 09/2013
4Matrix Metalloproteinases (MMPs)IBA
08/2015 - 01/2006
4TetrahydropapaverolineIBA
09/2010 - 11/2003
4Peroxynitrous Acid (Peroxynitrite)IBA
08/2009 - 10/2004
4GinsenosidesIBA
02/2009 - 11/2002
4Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
02/2005 - 01/2002
3sulforaphaneIBA
05/2022 - 06/2010
3Conditioned Culture MediaIBA
03/2022 - 01/2018
3Biological ProductsIBA
01/2022 - 12/2008
3Interleukin-6 (Interleukin 6)IBA
01/2022 - 09/2014
3p38 Mitogen-Activated Protein KinasesIBA
01/2022 - 11/2003
3N-chlorotaurineIBA
05/2021 - 01/2018
3Protein Kinases (Protein Kinase)IBA
03/2021 - 06/2010
3Glutathione Transferase (Glutathione S-Transferase)IBA
03/2021 - 04/2008
3quinone (benzoquinone)IBA
03/2021 - 06/2010
3Cyclin D1IBA
01/2021 - 03/2014
3resolvin D1IBA
01/2021 - 09/2013
3Arachidonic Acid (Vitamin F)IBA
01/2021 - 04/2008

Therapy/Procedure

26Chemoprevention
05/2022 - 01/2003
11Therapeutics
11/2022 - 09/2009
7Oral Administration
03/2021 - 02/2003
3Drug Therapy (Chemotherapy)
03/2021 - 11/2020
3Intraperitoneal Injections
01/2021 - 03/2020